A7098612
Quinapril hydrochloride , 98% , 82586-55-8
Synonym(s):
(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride;Quinapril hydrochloride
CAS NO.：82586-55-8
Empirical Formula: C25H31ClN2O5
Molecular Weight: 474.98
MDL number: MFCD00889215
EINECS: 620-479-5
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB639.20 | In Stock |
|
| 1G | RMB1592.00 | In Stock |
|
| 5G | RMB4784.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 120-130°C |
| alpha | D23 +14.5° (c = 1.2 in ethanol) (Klutchko); D25 +15.4° (c = 2 in methanol) (Goel, Krolls) |
| storage temp. | 2-8°C |
| solubility | H2O: >10mg/mL |
| form | solid |
| color | white |
Description and Uses
Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H303-H361 |
| Precautionary statements | P201-P202-P270-P281-P301+P312-P308+P313-P403-P501c |
| Safety Statements | 22-24/25 |
| WGK Germany | 2 |
| RTECS | NW7176000 |
| HS Code | 2933492250 |
| Toxicity | Freely sol in aq solvents. LD50 in male, female mice, rats (mg/kg): 1739, 1840, 4280, 3541 orally; 504, 523, 158, 107 i.v. (Kaplan, 1989) |
