Quinoline , AR,96% , 91-22-5
Synonym(s):
1-Azanaphthalene;1-Benzazine;2,3-Benzopyridine;Quinoline
CAS NO.：91-22-5
Empirical Formula: C9H7N
Molecular Weight: 129.16
MDL number: MFCD00006736
EINECS: 202-051-6
PRODUCT Properties
| Melting point: | -17--13 °C (lit.) |
| Boiling point: | 113-114 °C/11 mmHg (lit.)
237 °C (lit.) |
| Density | 1.093 g/mL at 25 °C (lit.) |
| vapor density | 4.5 (vs air) |
| vapor pressure | 0.07 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 214 °F |
| storage temp. | Store below +30°C. |
| solubility | 6g/l |
| pka | 4.9(at 20℃) |
| form | Liquid |
| color | Purple to dark grey |
| PH | 7.3 (5g/l, H2O, 20℃) |
| Odor | Strong, unpleasant. |
| explosive limit | 1.2-7%(V) |
| Odor Type | medicinal |
| Water Solubility | slightly soluble |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 14,8068 |
| BRN | 107477 |
| Dielectric constant | 2.6（-180℃） |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. May discolour on exposure to light. Hygroscopic - protect from moisture. Reacts violently and unpredictably with some materials, especially strong oxidizing agents. |
| InChIKey | SMWDFEZZVXVKRB-UHFFFAOYSA-N |
| LogP | 2.04 at 22℃ |
Description and Uses
Quinoline is a colourless hygroscopic liquid with characteristic odour. On exposure
to light, it turns brown in colour. Quinoline decomposes on heating, and on burning
produces toxic fumes including nitrogen oxides. Quinoline reacts with strong oxidants,
acids, and anhydrides. Quinoline is only slightly soluble in cold water but dissolves readily
in hot water and most organic solvents. Quinoline is combustible. It gives off irritating
or toxic fumes (or gases) in a fire. Quinoline is incompatible with strong acids, oxidisers,
dinitrogen tetroxide, linseed oil, thionyl chloride, maleic anhydride, and perchromates
and reacts violently with most incompatibles. Quinoline is used extensively in the manufacturing
of dyes, preparation of hydroxyquinoline sulphate and niacin, as a solvent for
resins and terpenes, and as an intermediate in the manufacture of other products.
Quinoline is used mainly as an intermediate in the manufacture of other several products,
as a catalyst, as a corrosion inhibitor, in metallurgical processes, in the manufacture of
dyes, as a preservative for anatomical specimens, in polymers and agricultural chemicals,
and as a solvent for resins and terpenes. Quinoline is also used as an anti-malarial medicine.
Because of its solubility in water, quinoline has significant potential for mobility in the
environment, which may promote water contamination. Potential exposure to quinoline
also occurs from the inhalation of cigarette smoke. Quinoline breaks down quickly in the
atmosphere and water.
Quinoline is used in the manufacture of dyesand hydroxyquinoline salts; as a solvent forresins and terpenes; and therapeutically as anantimalarial agent. It occurs in coal tar insmall amounts.
Safety
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301-H312-H315-H319-H341-H350-H411 |
| Precautionary statements | P202-P273-P280-P301+P310-P302+P352+P312-P305+P351+P338 |
| Hazard Codes | Xn,N,T |
| Risk Statements | 21/22-38-41-68-40-37/38-51/53-36/38-45 |
| Safety Statements | 26-36/37/39-36-23-61-45-53 |
| RIDADR | UN 2656 6.1/PG 3 |
| WGK Germany | 2 |
| RTECS | VA9275000 |
| F | 8 |
| Autoignition Temperature | 896 °F |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29334900 |
| Toxicity | LD50 orally in rats: 460 mg/kg (Smyth) |
