Quinidine Sulfate , 98% , 6591-63-5

Synonym(s):
Quinidine sulfate salt dihydrate

CAS NO.：6591-63-5

Empirical Formula: C20H26N2O6S

Molecular Weight: 422.5

MDL number: MFCD00149346

EINECS: 678-472-8

PRODUCT Properties

• Melting point: 212-214 °C (dec.)(lit.)
• alpha: [α]D20 +260～+270° (c=5, dil. HCl.10min)
• refractive index: 275 ° (C=2, 0.1mol/L HCl)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Slightly soluble in water, soluble in boiling water and in ethanol (96 per cent), practically insoluble in acetone.
• color: White to Off-White
• Water Solubility: Soluble in chloroform, water (11 mg/ml at 20°C), alcohol, and ethanol (50 mg/ml).
• Sensitive: Light Sensitive
• Merck: 14,8060
• InChIKey: AKYHKWQPZHDOBW-ZAXYGKDDNA-N
• SMILES: [C@@H]([C@@]1([H])C[C@@H]2CC[N@]1C[C@@H]2C=C)(C1=CC=NC2=CC=C(OC)C=C12)O.S(O)(O)(=O)=O |&1:0,1,4,7,9,r|
• CAS DataBase Reference: 6591-63-5(CAS DataBase Reference)

Description and Uses

Quinidine sulfate dihydrate is a diastereomer of quinine and a Na+ channel blocker. Also a class I antiarrhythmic drug. Quinidine sulfate dihydrate is a white, odorless crystalline substance that has a bitter flavor. It has limited solubility in water and alcohol but dissolves easily in chloroform and ether. This compound is effective against bacteria resistant to erythromycin, including staphylococci and streptococci, and works by inhibiting cellular ATPases.

antiarrhythmic, antimalarial

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: Xn
• Risk Statements: 22-20/21/22
• Safety Statements: 13-36
• RIDADR: UN 2811 6.1/PG III
• WGK Germany: 3
• RTECS: VA5605000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 2939200050