PRODUCT Properties
| Melting point: | 81-84 °C (lit.) |
| Boiling point: | 237.24°C (rough estimate) |
| Density | 1.2769 (rough estimate) |
| refractive index | 1.7000 (estimate) |
| RTECS | DM1235000 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in DMSO (up to 30mg/ml) |
| pka | 2.09±0.30(Predicted) |
| form | Crystalline Powder |
| color | Yellow to beige or light brown |
| Water Solubility | slightly soluble |
| BRN | 607843 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
Description and Uses
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2?Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
1-Aminobenzotriazole has been used as a cytochrome P450 inhibitor to study the effects of estrogen on H2O2-induced premature senescence of vascular smooth muscle cells from old rats It has also been used to study the estrogen receptor-mediated effects of 17β-estradiol.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29349990 |
