Bacitracin , 10mMinWater , 1405-87-4

Synonym(s):
Altracin, PDI Inhibitor I, Protein Disulfide Isomerase Inhibitor I;Bacitracin;Bacitracin - CAS 1405-87-4 - Calbiochem

CAS NO.：1405-87-4

Empirical Formula: C66H102N17O16S

Molecular Weight: 1421.69

MDL number: MFCD27976769

EINECS: 215-786-2

PRODUCT Properties

• Melting point: 221-225°C
• Density: 1.0166 (rough estimate)
• refractive index: 1.6700 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: H₂O: 50 mg/mL, clear to very slightly hazy, deep yellow
• form: Powder
• color: white to faintly beige
• Odor: odorless or acetic odor
• Water Solubility: soluble
• Merck: 13,936
• LogP: -0.050 (est)

Description and Uses

Bacitracin is a mixture of similar peptides produced by fermentation of the bacterium Bacillus subtil is. The A-type component predominates. Its mode of action is to inhibit both peptidoglycan biosynthesis at a late stage (probably at the dephosphorylation of the phospholipid carrier step) and disruptions of plasma membrane function.

antibiotic agent effective against gram-positive organisms and spirochetes; in products for topieal treatment, ear medications and ophthalmie drugs

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H317
• Precautionary statements: P260-P271-P272-P280g-P302+P352-P304+P340-P312-P363-P403+P233-P501c
• Hazard Codes: Xn
• Risk Statements: 20/21/22
• Safety Statements: 22-24/25-45-36
• WGK Germany: 2
• RTECS: CP0175000
• F: 21
• TSCA: Yes
• HS Code: 29419090
• Toxicity: LD50 oral in guinea pig: 2gm/kg