A7046458
Apigenin7-glucuronide , 10mMinDMSO , 29741-09-1
Synonym(s):
4′,5,7-Trihydroxyflavone 7-glucuronide;Apigenin 7-glucuronide;Apigenin 7-O-β-glucuronide;Scutellarin
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | >300℃ |
Boiling point: | 841.8±65.0 °C(Predicted) |
Density | 1.737 |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | DMSO : 65 mg/mL (145.62 mM; Need ultrasonic) |
form | powder |
pka | 2.73±0.70(Predicted) |
color | Yellowish |
InChIKey | JBFOLLJCGUCDQP-ZFORQUDYSA-N |
Description and Uses
Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22 |
WGK Germany | 3 |