A7043358
DonepezilHCl , 10mMinWater , 120011-70-3
Synonym(s):
(±)-2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride;1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride;2,3-Dihydro-5,6-dimethoxy-2-{[1-(phenylmethyl)-4-piperidinyl]methyl}-1H-inden-1-one;Donepezil hydrochloride;E2020
CAS NO.：120011-70-3
Empirical Formula: C24H30ClNO3
Molecular Weight: 415.95
MDL number: MFCD00881312
EINECS: 620-543-2
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 220-222°C |
| storage temp. | room temp |
| Water Solubility | Soluble in water |
| solubility | insoluble in EtOH; insoluble in DMSO; ≥10.4 mg/mL in H2O |
| form | powder |
| color | white to off-white |
| Merck | 14,3419 |
| Stability: | Hygroscopic |
| InChI | InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H |
| InChIKey | XWAIAVWHZJNZQQ-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(OC)C(OC)=C2)CC1CC1CCN(CC2=CC=CC=C2)CC1.[H]Cl |
| CAS DataBase Reference | 120011-70-3(CAS DataBase Reference) |
Description and Uses
Donepezil hydrochloride is an inhibitor of acetylcholinesterase with a labelled nootropic. It has been used in dose-response experiment to study its efficacy in ameliorating nicotine withdrawal-induced deficits in contextual conditioning in mice. It has also been intraperitoneally injected into rats to study its ability to improve social behavioral deficits, repetitive behavior and hyperactivity. Labeled Donepezil, intended for use as an internal standard for the quantification of Donepezilby GC- or LC-mass spectrometry.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H300-H319 |
| Precautionary statements | P264-P270-P280-P301+P310-P305+P351+P338-P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN 2811 |
| WGK Germany | 1 |
| RTECS | NK8927885 |
| HS Code | 2933.39.9200 |
| HazardClass | 6.1 |
| PackingGroup | II |
