Home Categories API Cetirizinedihydrochloride
A7041658

Cetirizinedihydrochloride , 10mMinDMSO , 83881-52-1

Synonym(s):
CE;Cetirizine dihydrochloride;CET;CTZ;[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

CAS NO.:83881-52-1

Empirical Formula: C21H26Cl2N2O3

Molecular Weight: 425.35

MDL number: MFCD00941428

EINECS: 620-533-8

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 110-115°C
storage temp.  2-8°C
solubility  H2O: soluble5mg/mL, clear
form  powder
color  white to beige
Water Solubility  Soluble in water, DMSO, ethanol, and methanol.
Merck  14,2022
BCS Class 1,3
Stability: Hygroscopic
InChIKey PGLIUCLTXOYQMV-UHFFFAOYSA-N
CAS DataBase Reference 83881-52-1(CAS DataBase Reference)
EPA Substance Registry System Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) (83881-52-1)

Description and Uses

Cetirizine hydrochloride is a once-daily, non-sedating antihistamine useful in the treatment of allergic rhinitis, urticaria and conjunctivitis. It is reported to be more effective than most other agents in this category such as terfenadine and astemizole.

Cetirizine hydrochloride is a nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. It is Cetirizine is an antihistamine medicine that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
RIDADR  3249
WGK Germany  3
RTECS  AG0977500
HazardClass  6.1(b)
PackingGroup  III
HS Code  29339900

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