Capsaicin , 10mMinDMSO , 404-86-4
Synonym(s):
[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide;8-Methyl-N-vanillyl-trans-6-nonenamide;Capsaicin
CAS NO.：404-86-4
Empirical Formula: C18H27NO3
Molecular Weight: 305.41
MDL number: MFCD00017259
EINECS: 206-969-8
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB239.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 62-65 °C(lit.) |
| Boiling point: | 210-220 C |
| Density | 1.1037 (rough estimate) |
| refractive index | 1.5100 (estimate) |
| FEMA | 3404 | CAPSAICIN |
| Flash point: | 113 °C |
| storage temp. | 2-8°C |
| solubility | H2O: insoluble |
| form | Off-white solid |
| pka | 9.76±0.20(Predicted) |
| color | Off-white |
| Odor | mild warm herbal |
| Odor Type | herbal |
| Water Solubility | insoluble |
| Merck | 14,1768 |
| BRN | 2816484 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
| LogP | 4.00 |
| CAS DataBase Reference | 404-86-4(CAS DataBase Reference) |
| EPA Substance Registry System | Capsaicin (404-86-4) |
Description and Uses
Capsaicin has a mild, warm-herbaceous odor and a burning pungent taste (at 10 ppm). It is used in compounded flavors for sauces where the pungent note is desired. This substance is present in several species of Capsicum (Family, Solanaceae). The sensation of pain, accompanied by irritation and inflammation, is due to substance P depletion from sensory (afferent) nerve fibers. These properties are used to study the physiology of pain and the effects as a counterirritant and gastrointestinal stimulant. This substance may be prepared from 3-chloro-2-isopropyltetrahydropyran; biosynthesis from Capsicum frutescens; separation form cis-capsaicin, pelargonic acid vanilamide, and dihydrocapsaicin, reaction of capsaicin.
analgesic (topical), depletes Substance P, neurotoxic
Safety
| Symbol(GHS) |    GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300-H315-H317-H318-H334-H335 |
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | T,T+ |
| Risk Statements | 25-37/38-41-42/43-36/37/38 |
| Safety Statements | 22-26-28-36/39-45-36/37/39 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | RA8530000 |
| F | 10-21 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29399990 |
| Hazardous Substances Data | 404-86-4(Hazardous Substances Data) |
| Toxicity | LD50 oral in mouse: 47200ug/kg |
