A7025558
CefpodoximeProxetil , 10mMinDMSO , 87239-81-4
Synonym(s):
(RS)1(isopropoxycarbonyloxy) ethyl (+)-(6R,7R)-7-[2-(2-amino-4- thiazolyl)-2-{(Z)methoxyimino}acetamido]-3methoxymethyl-8-oxo-5-thia-1-azabicyclo [4.2.0]oct-2-ene- 2-carboxylate;Cefpodoxime proxetil
CAS NO.:87239-81-4
Empirical Formula: C21H27N5O9S2
Molecular Weight: 557.6
MDL number: MFCD00865088
EINECS: 1308068-626-2
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 111-113°C |
Density | 1.58±0.1 g/cm3(Predicted) |
RTECS | XI0367370 |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | Soluble in DMSO |
form | Solid |
pka | 8.13±0.60(Predicted) |
color | White to Pale Yellow |
Sensitive | Light Sensitive |
InChIKey | LTINZAODLRIQIX-FBXRGJNPSA-N |
SMILES | N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(COC)=C2C(OC(OC(OC(C)C)=O)C)=O |
CAS DataBase Reference | 87239-81-4(CAS DataBase Reference) |
Description and Uses
Cefpodoxime proxetil is an orally active, broad-spectrum cephalosporin especially useful in the treatment of bacterial infections in children. It is a prodrug converted by esterases in the GI walls to cefpodoxime, which reportedly has a bacteriostatic spectrum comparable to injectable third-generation cephem antibiotics.
A metabolite of Cefpodoxime Proxetil. An antibacterial.
Safety
Symbol(GHS) | GHS08 |
Signal word | Warning |
Hazard statements | H317-H334 |
Precautionary statements | P261-P280g-P284-P304+P340-P342+P311a-P501a |
Hazard Codes | Xi |
Risk Statements | 36/37/38-42/43 |
Safety Statements | 22-26-36/37/39 |
WGK Germany | 3 |
HS Code | 30042000 |
Toxicity | LD50 in male, female mice, male, female rats (mg/kg): >10000, >10000, >2000, >2000 s.c., 3502, 2535, >4000, >4000 i.p.; >8000, >8000, >4000, >4000 orally (Nakao, 1988) |