Benzbromarone , 10mMinDMSO , 3562-84-3
Synonym(s):
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran
CAS NO.：3562-84-3
Empirical Formula: C17H12Br2O3
Molecular Weight: 424.08
MDL number: MFCD00078962
EINECS: 222-630-7
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 151° |
| Boiling point: | 514.1±50.0 °C(Predicted) |
| Density | 1.6211 (rough estimate) |
| refractive index | 1.6010 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| pka | 4.66±0.25(Predicted) |
| form | Solid |
| color | White to Light yellow |
| Merck | 14,1065 |
| InChIKey | WHQCHUCQKNIQEC-UHFFFAOYSA-N |
Description and Uses
Benzbromarone,a non-competitive inhibitor of xanthine oxidase，is apotent uricosuric drug used in the treatment of gout.
Benzbromarone is a benzofuran derivative chemically related to amiodarone. It increases uric acid excretion by non-specificallyinhibiting its tubular reabsorption.
lt is used in patients with venous disorders to prevent,retard,or reverse varicose degenerative changes in the vessel wall.
Benzbromarone causes diarrhea (3-4% of patients), urate and oxalate stones,urinary sand,renal colic，and allergy in a small number of patients.Liver damage, which reverses after withdrawal, has been described (SEDA-18,108).
Coronarodilatator;Uric acid transport inhibitor
