PRODUCT Properties
| Melting point: | 149-152 °C (lit.) |
| Boiling point: | 315.5±25.0 °C(Predicted) |
| Density | 1.274 (estimate) |
| refractive index | 1.5500 (estimate) |
| Flash point: | 250°C |
| storage temp. | Store below +30°C. |
| solubility | methanol: soluble25mg/mL |
| pka | 10.1(at 25℃) |
| form | Powder, Crystals and/or Chunks |
| color | White to off-white |
| Water Solubility | 4.3 g/L (16 ºC) |
| BRN | 1100566 |
| InChIKey | KHBQMWCZKVMBLN-UHFFFAOYSA-N |
Description and Uses
Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.
