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A7011258

Benzenesulfonamide , 10mMinDMSO , 98-10-2

Synonym(s):
Benzenesulfonamide

CAS NO.:98-10-2

Empirical Formula: C6H7NO2S

Molecular Weight: 157.19

MDL number: MFCD00007930

EINECS: 202-637-1

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 149-152 °C (lit.)
Boiling point: 315.5±25.0 °C(Predicted)
Density  1.274 (estimate)
refractive index  1.5500 (estimate)
Flash point: 250°C
storage temp.  Store below +30°C.
solubility  methanol: soluble25mg/mL
pka 10.1(at 25℃)
form  Powder, Crystals and/or Chunks
color  White to off-white
Water Solubility  4.3 g/L (16 ºC)
BRN  1100566
InChIKey KHBQMWCZKVMBLN-UHFFFAOYSA-N

Description and Uses

Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  DA9380000
TSCA  Yes
HS Code  29350090
Toxicity LD50 orally in Rabbit: 991 mg/kg

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