Chlorhexidinediacetatesalthydrate , 10mMinDMSO , 56-95-1
Synonym(s):
Chlorhexidine diacetate;Chlorhexidine diacetate salt
CAS NO.:56-95-1
Empirical Formula: C26H38Cl2N10O4
Molecular Weight: 625.55
MDL number: MFCD00012532
EINECS: 200-302-4
Pack Size | Price | Stock | Quantity |
1ml | RMB159.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 153-156°C |
storage temp. | 2-8°C |
solubility | H2O: 15 mg/mL, clear |
form | Solid |
color | White to Almost white |
Water Solubility | 1.9 g/100 mL (20 ºC) |
Merck | 14,2091 |
InChIKey | GHXZTYHSJHQHIJ-UHFFFAOYSA-N |
LogP | 4.931 (est) |
Description and Uses
Chlorhexidine Diacetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. Aqueous solutions of chlorhexidine are most stable within the pH range of 5-8. Above pH 8.0 chlorhexidine base is precipitated and in more acid conditions there is gradual deterioration of activity because the compound is less stable. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
Safety
Symbol(GHS) | GHS07,GHS08,GHS09 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H371-H410 |
Precautionary statements | P260-P273-P301+P312-P302+P352-P305+P351+P338-P308+P311 |
Hazard Codes | Xn,Xi,N |
Risk Statements | 22-43-36/37/38-50/53 |
Safety Statements | 36/37-36-26-61-60 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | DU1930000 |
F | 8-10 |
HazardClass | 9 |
PackingGroup | III |
HS Code | 2925294500 |
Toxicity | LD50 orally in mice: 2 g/kg (Davies) |