PRODUCT Properties
| Melting point: | 40-42 °C(lit.) |
| Boiling point: | 218-219 °C(lit.) |
| Density | 1,011 g/cm3 |
| vapor density | 4.2 (vs air) |
| vapor pressure | 0.13 mm Hg ( 20 °C) |
| FEMA | 3156 | P-ETHYLPHENOL |
| refractive index | 1.5330 |
| Flash point: | 213 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 4.9g/l |
| form | Crystalline Mass or Crystals |
| pka | pK1:10.0 (25°C) |
| Specific Gravity | 1.0123 (20℃) |
| color | White to brownish |
| Odor | at 1.00 % in dipropylene glycol. phenolic castoreum smoke guaiacol |
| Odor Type | smoky |
| Water Solubility | 4.9 g/L (25 ºC) |
| JECFA Number | 694 |
| BRN | 1363317 |
| Stability: | Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents. |
| InChIKey | HXDOZKJGKXYMEW-UHFFFAOYSA-N |
| LogP | 2.1 at 20℃ and pH7 |
| Surface tension | 54mN/m at 998g/L and 22℃ |
| CAS DataBase Reference | 123-07-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 4-ethyl-(123-07-9) |
| EPA Substance Registry System | p-Ethylphenol (123-07-9) |
Description and Uses
4-Ethylphenol (4-EP) is a phenolic compound with the formula C8H10O. It is colorless or white needles with a powerful woody-phenolic and yet somewhat sweet odor and tends to be yellow on exposure to light. It is slightly solouble in water, solouble in alcohol, ether and benzene and carbon disulfide. It is found in arabica coffee and can be produced in wine and beer by the spoilage yeast Brettanomyces. It is the starting material for the production of 4-vinylphenol and of various antioxidants and can also be used as an intermediate for pharmaceuticals and dyes. It is an industrially versatile commodity chemical widely applied in the pharmaceutical and food industries.
4-Ethylphenol is suitable for use in the determination of 4-ethylguaiacol and 4-ethylphenol in the aroma of red wines using headspace-solid-phase microextraction method. It is a chemical reagent used in the synthesis of 5-HT1A receptor agonists endowed with antinociceptive activity in vivo. It is also used in the preparation of isopropylamides as potent and noncovalent proteosome inhibitors.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi,C |
| Risk Statements | 36/37/38-R36/37/38-34 |
| Safety Statements | 26-36-S36-S26-45-36/37/39 |
| RIDADR | UN 2430 8/PG 3 |
| WGK Germany | 3 |
| RTECS | SL4040000 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29071900 |
| Hazardous Substances Data | 123-07-9(Hazardous Substances Data) |
