Dirithromycin , 10mMinDMSO , 62013-04-1
Synonym(s):
[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxy)ethylidene]oxy]erthromycin; LY-237216
CAS NO.：62013-04-1
Empirical Formula: C42H78N2O14
Molecular Weight: 835.07
MDL number: MFCD00865041
EINECS: 624-080-7
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 186-189° (dec) (Counter) |
| Boiling point: | 871.8±65.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Very slightly soluble in water, very soluble in methanol and in methylene chloride |
| pka | 9.0 in 66% aq dimethyl fluoride |
| form | solid |
| color | white to off-white |
Description and Uses
Dirithromycin, an orally active oxazine derivative of erythromycin, is a secondgeneration macrolide antibiotic. It was first introduced in Spain for the treatment of respiratory tract, skin and soft tissue infections. It is safe and effective in treating acute bronchitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, pharyngitis, and tonsillitis. Dirithromycin has been reported to have a similar antimicrobial spectrum and potency to erythromycin. However, compared to other macrolide antibiotics, dirithromycin has improved oral bioavailability, higher tissue permeability and longer duration of action. The once-daily therapy regiment is advantageous in terms of patient compliance and is a good alternative for patients who are unable to take penicillin.
antihypertensive
