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A6963258

BCTC , 10mMinDMSO , 393514-24-4

Synonym(s):
4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide

CAS NO.:393514-24-4

Empirical Formula: C20H25ClN4O

Molecular Weight: 372.89

MDL number: MFCD08690556

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 150-152℃
Boiling point: 561.6±50.0 °C(Predicted)
Density  1.229±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: >10mg/mL
pka 13.95±0.70(Predicted)
form  powder
color  white to beige
Sensitive  Light Sensitive
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months.
InChIKey ROGUAPYLUCHQGK-UHFFFAOYSA-N

Description and Uses

BCTC (393514-24-4) is a vanilloid receptor I (TRPV1) blocker, IC50 = 35 nM for capsaicin-induced and 6 nM for acid-induced TRPV1 activation. Displays analgesic activity in rat models of neuropathic pain. BCTC is orally active and cell permeable.

BCTC is a antagonists of TRPA1 and TRPV1, a non-selective cation channel gated by noxious heat, vanilloids and extracellular protons. BCTC inhibits both capsaicin and proton activation.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264b-P270-P301+P312-P330-P403-P501c
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3

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