Aceclofenac , 10mMinDMSO , 89796-99-6

Synonym(s):
2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester;;Aceclofenac

CAS NO.：89796-99-6

Empirical Formula: C16H13Cl2NO4

Molecular Weight: 354.18

MDL number: MFCD00864296

EINECS: 641-844-5

PRODUCT Properties

• Melting point: 149-153°C
• Boiling point: 486.0±45.0 °C(Predicted)
• Density: 1.455±0.06 g/cm3(Predicted)
• RTECS: CY1577900
• storage temp.: 2-8°C
• solubility: Soluble in DMSO
• form: powder
• pka: 2.60±0.10(Predicted)
• color: off-white to light tan
• Water Solubility: 32mg/L(32 ºC)
• Merck: 14,22
• InChIKey: MNIPYSSQXLZQLJ-UHFFFAOYSA-N
• CAS DataBase Reference: 89796-99-6(CAS DataBase Reference)
• EPA Substance Registry System: Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester (89796-99-6)

Description and Uses

Aceclofenac is a nonsteroidal antiinflammatory agent with analgesic and antipyretic properties. It is reported to be useful in the treatment of osteoarthritis, rheumatoid arthritis and pain associated with minor surgical procedures. Compared to ketoprofen in the treatment of rheumatoid arthritis, aceclofenac is substantially faster acting.

Aceclofenac is a non-steroidal, anti-inflammatory drug (NSAID) with potent inhibitory activity in several models of inflammation. It is used for the treatment of osteoarthritis and rheumatoid arthritis. It is a Biopharmaceutics classification system class II (BCS class I) drug which has an intermediate half-life of 3-4h and undergoes substantial first pass metabolism. aceclofenac is available either in oral form (tablet) or in topical form (gel).

Safety

• Symbol(GHS): GHS06,GHS09
• Signal word: Danger
• Hazard statements: H301-H319-H410
• Precautionary statements: P273-P301+P310+P330-P305+P351+P338
• Hazard Codes: T,N
• Risk Statements: 25-36-50/53
• Safety Statements: 26-45-60-61
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29224999