CalciumLevofolinate , 10mMinWater , 80433-71-2
CAS NO.:80433-71-2
Empirical Formula: C20H25CaN7O7
Molecular Weight: 515.54
MDL number: MFCD00865527
EINECS: 801-530-2
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 240-2500C (dec) |
alpha | D20 -15.1° (c = 1.82) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | Slightly soluble in water, practically insoluble in acetone and in ethanol (96 per cent). |
form | Solid |
color | Off-White to Pale Beige |
Stability: | Hygroscopic, Light Sensitive |
Description and Uses
L-Folinic acid is a reduced folic acid and isomer of DL-folinic acid . DL-Folinic acid is a racemic mixture of D-folinic acid and L-folinic acid that has been used to prevent toxicity following therapy with high-dose methotrexate , to enhance the antitumor activity of 5-fluorouracil , and as a folate supplement. Clinical studies demonstrate that formulations containing L-folinic acid have similar efficacy and tolerability as those contianing DL-folinic acid and have been used interchangeably for modification of antitumor activity of 5-fluorouracil, while D-folinic acid is inactive.
intermediate from Folic Acid metabolism
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |