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A6947958

CalciumLevofolinate , 10mMinWater , 80433-71-2

CAS NO.:80433-71-2

Empirical Formula: C20H25CaN7O7

Molecular Weight: 515.54

MDL number: MFCD00865527

EINECS: 801-530-2

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 240-2500C (dec)
alpha  D20 -15.1° (c = 1.82)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  Slightly soluble in water, practically insoluble in acetone and in ethanol (96 per cent).
form  Solid
color  Off-White to Pale Beige
Stability: Hygroscopic, Light Sensitive
CAS DataBase Reference 80433-71-2(CAS DataBase Reference)

Description and Uses

L-Folinic acid is a reduced folic acid and isomer of DL-folinic acid . DL-Folinic acid is a racemic mixture of D-folinic acid and L-folinic acid that has been used to prevent toxicity following therapy with high-dose methotrexate , to enhance the antitumor activity of 5-fluorouracil , and as a folate supplement. Clinical studies demonstrate that formulations containing L-folinic acid have similar efficacy and tolerability as those contianing DL-folinic acid and have been used interchangeably for modification of antitumor activity of 5-fluorouracil, while D-folinic acid is inactive.

intermediate from Folic Acid metabolism

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

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