Paraldehyde , ≥95% , 123-63-7
Synonym(s):
Paraldehyde;2,4,6-Trimethyl-1,3,5-trioxane;2,4,6-Trimethyl-1,3,5-trioxacyclohexane;Paracetaldehyde;Acetaldehyde trimer
CAS NO.：123-63-7
Empirical Formula: C6H12O3
Molecular Weight: 132.16
MDL number: MFCD00036208
EINECS: 204-639-8
PRODUCT Properties
| Melting point: | 12 °C |
| Boiling point: | 65-82 °C |
| Density | 0.994 g/mL at 20 °C (lit.) |
| vapor density | 1.52 (vs air) |
| vapor pressure | 25.89 psi ( 55 °C) |
| FEMA | 4010 | PARALDEHYDE |
| refractive index | n |
| Flash point: | 30 °F |
| storage temp. | 2-8°C |
| solubility | 120g/l |
| pka | 16(at 25℃) |
| form | solution |
| Specific Gravity | 0.994 |
| color | Colorless liquid |
| Odor | disagreeable taste, aromatic odor |
| explosive limit | 1.3-17.0%(V) |
| Water Solubility | 125 g/L (25 ºC) |
| Merck | 13,7098 |
| BRN | 80142 |
| Dielectric constant | 14.5（20℃） |
| Stability: | Stable. Flammable. Incompatible with strong oxidizing agents, mineral acids. |
| InChIKey | SQYNKIJPMDEDEG-UHFFFAOYSA-N |
| LogP | 0.670 |
| CAS DataBase Reference | 123-63-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Paraldehyde(123-63-7) |
| EPA Substance Registry System | Paraldehyde (123-63-7) |
Description and Uses
Paraldehyde was first synthesized in 1829 by Wildenbusch and introduced into clinical practice in the United Kingdom by the Italian physician Vincenzo Cervello in 1882. Paraldehyde, a polymer of acetaldehyde, is a clear colorless or slightly yellow transparent liquid with a strong aromatic as well as a disagreeable taste that at low temperatures, it solidifies into a crystalline mass. This agent decomposes with strong into toxic products that may be released into water, soil, or atmosphere.
Paraldehyde is used in ethanol hangover prevention. It is also used in the treatment of rectal diseases in patients with delirium tremens.
Safety
| Symbol(GHS) |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210-P233-P240-P241-P242-P243 |
| Hazard Codes | F |
| Risk Statements | 11-R11-10 |
| Safety Statements | 9-16-29-33-S9-S33-S29-S16 |
| RIDADR | UN 1993 3/PG 2 |
| WGK Germany | 1 |
| RTECS | YK0525000 |
| Autoignition Temperature | 235 °C |
| HazardClass | 3.2 |
| PackingGroup | III |
| HS Code | 29125000 |
| Hazardous Substances Data | 123-63-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 1.65 g/kg (Figot) |
