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A6857712

Praziquantel , >98.0%(HPLC) , 55268-74-1

Synonym(s):
2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one;Praziquantel

CAS NO.:55268-74-1

Empirical Formula: C19H24N2O2

Molecular Weight: 312.41

MDL number: MFCD00058531

EINECS: 259-559-6

Pack Size Price Stock Quantity
5G RMB46.40 In Stock
25G RMB120.80 In Stock
100G RMB357.60 In Stock
500g RMB1339.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 136-138 C
Boiling point: 1377℃
Density  1.1209 (rough estimate)
refractive index  1.5600 (estimate)
Flash point: >110°(230°F)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  ethanol: soluble5mg/mL
form  powder or crystals
pka -0.98±0.20(Predicted)
color  Crystals from EtOAc/hexane
Water Solubility  Freely soluble in ethanol or dichloromethane. Slightly soluble in water
Merck  13,7802
BRN  761557
BCS Class 2
EPA Substance Registry System Praziquantel (55268-74-1)

Description and Uses

Praziquantel (PZQ) is an isoquinoline derivative with most of the biological activity found in the levo enantiomer. The compound has no activity against nematodes, but it is highly effective against cestodes and trematodes.

Praziquantel is a potent anthelmintic used against schistosome and many cestode infestations. It is used to study voltage-gated Ca2+ channels and is a potential small molecule neurogenic.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  16-26-36/37/39-45-24/25
WGK Germany  1
RTECS  UQ4150000
HS Code  29339900
Toxicity LD50 in mice, rats (mg/kg): 2000-3000 orally; >3000 s.c. (Muermann)

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