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A6813912

Phenazopyridine HCl , ≥98% , 136-40-3

Synonym(s):
2,6-Diamino-3-(phenylazo)pyridine hydrochloride;Phenazopyridine hydrochloride;Urodine

CAS NO.:136-40-3

Empirical Formula: C11H12ClN5

Molecular Weight: 249.7

MDL number: MFCD00035347

EINECS: 205-243-8

Pack Size Price Stock Quantity
5G RMB89.60 In Stock
25G RMB399.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 139°C
Boiling point: 394.6°C (rough estimate)
Density  1.2645 (rough estimate)
refractive index  1.6110 (estimate)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form  Liquid
color  Clear to hazy colorless to yellow
Water Solubility  0.01-0.1 g/100 mL at 20 ºC
Merck  14,7210
Stability: Light Sensitive
InChIKey QQBPIHBUCMDKFG-GEEYTBSJSA-N

Description and Uses

Phenazopyridine is an azo dye with analgesic properties. It decreases the bladder distension-induced firing rate of afferent bladder Aγ-fibers, but not C-fibers, in anesthetized rats when administered at a doses of 0.3, 1, and 3 mg/kg. Formulations containing phenazopyridine have been used as analgesics in the treatment of urinary tract infections.

Phenazopyridine hydrochloride has been used for 50 years as an analgesic drug either alone or in combination with other drugs to reduce pain associated with urinary tract infection. An azo dye used in urinary tract infections. Also used as a local anesthetic. Exposure to phenazopyridine hydrochloride occurs during manufacture and formulation.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H315-H319-H335-H351
Precautionary statements  P202-P261-P301+P312-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xn,C
Risk Statements  22-36/37/38-40-34-42/43
Safety Statements  26-36/37-45-36/37/39-27-22
RIDADR  2811
WGK Germany  3
RTECS  US7875000
HS Code  29333990
Toxicity LD50 orally in rats: 403 mg/kg (Becker, Swift)

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