Piperacillin Sodium , ≥98%(N) , 59703-84-3

CAS NO.：59703-84-3

Empirical Formula: C23H26N5NaO7S

Molecular Weight: 539.54

MDL number: MFCD00917471

EINECS: 261-868-6

PRODUCT Properties

• Melting point: 183-185 C (dec.)
• Boiling point: 793℃
• refractive index: 180 ° (C=0.8, H2O)
• storage temp.: Inert atmosphere,2-8°C
• solubility: H₂O: 50 mg/mL, clear, colorless to faintly yellow
• form: Solid
• color: White to Almost white
• Water Solubility: Soluble in ethanol, water and methanol.
• Merck: 14,7463
• BRN: 5373920
• Stability: Hygroscopic
• InChIKey: WCMIIGXFCMNQDS-IDYPWDAWSA-M

Description and Uses

Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.

A broad spectrum antibiotic targeting a wide range of susceptible gram positive and gram negative bacteria. Piperacillin sodium salt is an antibiotic. It is used in pharmacokinetic studies to optimize antimicrobial therapy and in hypersensitivity reactions. It is involved in the study of multidrug-resistant organisms. It acts as an antibiotic related to penicillin.

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H317-H334
• Precautionary statements: P261-P280g-P284-P304+P340-P342+P311a-P501a
• Hazard Codes: Xn
• Risk Statements: 42/43
• Safety Statements: 22-36/37-45
• WGK Germany: 2
• RTECS: XI0180000
• HS Code: 29411099
• Toxicity: LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai)