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A6811812

Azacyclonol , ≥99% , 115-46-8

Synonym(s):
Azacyclonol;Diphenyl-4-piperidinemethanol

CAS NO.:115-46-8

Empirical Formula: C18H21NO

Molecular Weight: 267.37

MDL number: MFCD00066980

EINECS: 204-092-5

Pack Size Price Stock Quantity
5g RMB23.20 In Stock
25G RMB102.40 In Stock
100g RMB237.60 In Stock
500g RMB1023.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 160-163 °C
Boiling point: 410.55°C (rough estimate)
Density  1.0449 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.5100 (estimate)
storage temp.  Store below +30°C.
solubility  Chloroform, Methanol (Slightly, Sonicated)
pka 13.32±0.29(Predicted)
form  Solid
color  White to light beige
InChIKey ZMISODWVFHHWNR-UHFFFAOYSA-N
CAS DataBase Reference 115-46-8(CAS DataBase Reference)
NIST Chemistry Reference Azacyclonol(115-46-8)

Description and Uses

alpha,alpha-Diphenyl-4-piperidinomethanol is an important organic synthetic substance for the synthesis of diphenyl-4-piperidinomethanol. It is also used as a pharmaceutical intermediate in the preparation of terfenadine and Fexofenadine hydrochloride.

α-(4-Piperidyl)benzhydrol is a key intermediate in the synthesis of Fexofenadine (F322490). Fexofenadine EP Impurity E.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  WGK 3 highly water endangering
RTECS  TN0470000
HS Code  29333999

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