Phloretin , ≥98% , 60-82-2

Synonym(s):
β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone;2?,4?,6?-Trihydroxy-3- p-hydroxyphenylpropiophenone;2?,4?,6?-Trihydroxy-3-p-hydroxyphenylpropiophenone;2′,4′,6′-Trihydroxy-3-(4-hydroxyphenyl)propiophenone;3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone

CAS NO.：60-82-2

Empirical Formula: C15H14O5

Molecular Weight: 274.27

MDL number: MFCD00002288

EINECS: 200-488-7

PRODUCT Properties

• Melting point: ~260 °C
• Boiling point: 337.26°C (rough estimate)
• Density: 1.1827 (rough estimate)
• FEMA: 4390 | 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
• refractive index: 1.573-1.575
• storage temp.: 2-8°C
• solubility: Acetonitrile (Slightly), Methanol (Slightly)
• pka: 7.16±0.40(Predicted)
• form: Powder
• color: White to beige
• Odor: odorless
• Water Solubility: soluble
• Merck: 14,7326
• JECFA Number: 2022
• BRN: 1887240
• InChIKey: VGEREEWJJVICBM-UHFFFAOYSA-N
• LogP: 3.50

Description and Uses

Phloretin has been used:

• to study its effect on the 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose (2-NBDG) and 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-l-glucose (2-NBDLG) uptake
• to incubate microvesicles in order to inhibit GLUT1 (glucose transporter 1)-mediated transport in radioactive ligand up-take assay
• as a component of KRH buffer to stop glucose uptake by trophoblast cells in vitro

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 37/39-26-36
• WGK Germany: 3
• F: 3-10
• HazardClass: IRRITANT
• HS Code: 29145090