2,2,3,3,3-Pentafluoro-1-propanol , 98% , 422-05-9

Synonym(s):
PFPOH

Update time: 2022-07-08

Boiling point:	80 °C748 mm Hg(lit.)
Density	1.505 g/mL at 25 °C(lit.)
vapor pressure	62.055-324.857hPa at 24.93-54.78℃
refractive index	n20/D 1.288(lit.)
Flash point:	80-81°C
storage temp.	Flammables area
form	Powder, Crystals and/or Chunks
pka	12.45±0.10(Predicted)
color	White to off-white to light yellow
Specific Gravity	1.509
Water Solubility	Soluble in water.21.9 g/L at 25°C
BRN	1743133
InChIKey	PSQZJKGXDGNDFP-UHFFFAOYSA-N
LogP	1.23

2,2,3,3,3-Pentafluoro-1-propanol has been used:

as derivatization reagent in detection of unlabeled and ¹⁵N₂ -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS
as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS
preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides
to generate fluorinated α-keto ethers with alkenes and has wide applications in the expanding fluorous research area