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A6746212

Phloridzin dihydrate , 98% , 7061-54-3

CAS NO.:7061-54-3

Empirical Formula: C21H24O10

Molecular Weight: 436.41

MDL number: MFCD00006591

EINECS: 628-113-6

Pack Size Price Stock Quantity
20MG RMB31.20 In Stock
100mg RMB388.00 In Stock
1G RMB580.00 In Stock
5G RMB1744.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 113-114 °C(lit.)
alpha  -52 º (c=3, EtOH)
storage temp.  Inert atmosphere,2-8°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Solid
color  White to off-white
optical activity [α]20/D 52°, c = 3 in ethanol
BRN  66621
CAS DataBase Reference 7061-54-3(CAS DataBase Reference)

Description and Uses

Phloridzin dihydrate has been used as:

  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UC2080000
3-10-23

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