Home Categories Biochemical Engineering Pseudolaric Acid B
A6673012

Pseudolaric Acid B , Analysis standard product, 98% , 82508-31-4

Synonym(s):
(-)-Pseudolaric acid B;O-Acetylpseudolaric acid C;Pseudolarix acid B

CAS NO.:82508-31-4

Empirical Formula: C23H28O8

Molecular Weight: 432.46

MDL number: MFCD01746346

Pack Size Price Stock Quantity
20MG RMB439.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 166°C
Boiling point: 466.14°C (rough estimate)
Density  1.2108 (rough estimate)
refractive index  1.4480 (estimate)
storage temp.  2-8°C
solubility  methanol: soluble1mg/mL, clear, colorless
form  powder or crystals
pka 4.52±0.19(Predicted)
color  white to off-white
InChIKey VDGOFNMYZYBUDT-YCONPBHISA-N

Description and Uses

Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.

(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.

Safety

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H361fd
Precautionary statements  P201-P301+P310+P330
Hazard Codes  T
Risk Statements  25-62
Safety Statements  36/37-45-24/25
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HS Code  29329990
Hazardous Substances Data 82508-31-4(Hazardous Substances Data)

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