Home Categories Biochemical Engineering DL-α-Phenylglycine
A6631812

DL-α-Phenylglycine , 98% , 2835-06-5

Synonym(s):
(±)-α-Aminophenylacetic acid;DL-α-Phenylglycine

CAS NO.:2835-06-5

Empirical Formula: C8H9NO2

Molecular Weight: 151.17

MDL number: MFCD00064402

EINECS: 220-608-1

Pack Size Price Stock Quantity
25G RMB28.80 In Stock
100G RMB92.00 In Stock
500G RMB356.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 290 °C (subl.)(lit.)
alpha  [α]D20-0.5~+0.5゜ (c=5, dil. HCl)
Boiling point: 273.17°C (rough estimate)
Density  1.2023 (rough estimate)
refractive index  1.5810 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  almost transparency in Sodium hydroxide solution
pka 1.94±0.10(Predicted)
form  Crystalline Powder
color  White to off-white
Water Solubility  115g/L(100 ºC)
Merck  14,7291
BRN  3197862
InChIKey ZGUNAGUHMKGQNY-UHFFFAOYSA-N
CAS DataBase Reference 2835-06-5(CAS DataBase Reference)
NIST Chemistry Reference Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
EPA Substance Registry System 2-Phenylglycine (2835-06-5)

Description and Uses

2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.

DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  24/25-45-36/37/39-26-16
WGK Germany  3
TSCA  Yes
HS Code  29224999

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