1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt) , >99% , 325465-93-8
| Pack Size | Price | Stock | Quantity |
| 25MG | RMB1199.20 | In Stock |
|
| 100MG | RMB2399.20 | In Stock |
|
| 250MG | RMB5599.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 10 mg/ml with warming). |
| form | Waxy solid. |
| color | White |
| Water Solubility | Soluble in water up to 5mg/ml with sonication |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
Description and Uses
Lysophosphatidic acid (325465-93-8) is a multifunctional intercellular bioactive phospholipid.1?Stimulates the growth of a variety of cells including fibroblasts, vascular smooth muscle cells, endothelial cells and keratinocytes among others.1?Acts as a proliferative and anti-apoptotic factor.2?Lysophophatidic acid is an agonist at LPA1?(EDG-2), LPA2?(EDG-4) and LPA3?(EDG-7) receptors.3?LPA-primed astrocytes induce axonal outgrowth of cortical progenitors.4
It is an endogenous agonist for LPA1?and LPA2?receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells. LPA has also been described to potentiate acetylchloine receptor currents by G-protein-mediated activation of Ca2+-dependent/independent protein kinase C.
