Oseltamivir phosphate , ≥99% , 204255-11-8
Synonym(s):
(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate salt;GS4104;Oseltamivir phosphate
CAS NO.：204255-11-8
Empirical Formula: C16H31N2O8P
Molecular Weight: 410.4
MDL number: MFCD08059548
EINECS: 616-396-9
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB47.20 | In Stock |
|
| 250MG | RMB87.20 | In Stock |
|
| 500MG | RMB135.20 | In Stock |
|
| 1G | RMB207.20 | In Stock |
|
| 5G | RMB783.20 | In Stock |
|
| 25G | RMB3839.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 196-198°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble30mg/mL, clear |
| form | powder |
| color | white to beige |
| optical activity | [α]/D -26 to -36°, c = 1 in H2O |
| Water Solubility | Soluble in water (75 mM) |
| BCS Class | 1 (CLogP), 3
(LogP) |
| InChI | InChI=1/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/s3 |
| InChIKey | PGZUMBJQJWIWGJ-IFAKAUOZSA-N |
| SMILES | [C@@H]1(OC(CC)CC)C=C(C[C@H](N)[C@H]1NC(=O)C)C(=O)OCC.OP(O)(O)=O |&1:0,10,12,r| |
| CAS DataBase Reference | 204255-11-8(CAS DataBase Reference) |
Description and Uses
Oseltamivir phosphate (Tamiflu) was launched in the US and Switzerland for the treatment of influenza infections by all common strain viruses. It is an oral anti-viral drug approved for the treatment of acute, uncomplicated influenza in patients 2 weeks of age and older whose flu symptoms have not lasted more than two days. This product is approved to treat Type A and B influenza; however, the majority of patients included in the studies were infected with type A, the most common in the U.S. Efficacy of Tamiflu in the treatment of influenza in subjects with chronic cardiac disease and/or respiratory disease has not been established.
Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317-H319-H412 |
| Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 |
| HazardClass | IRRITANT |
| HS Code | 2924299500 |
