Ozagrel hydrochloride hydrate , ≥98%(HPLC) , 78712-43-3

Synonym(s):
(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate;OKY-046

CAS NO.：78712-43-3

Empirical Formula: C13H13ClN2O2

Molecular Weight: 264.71

MDL number: MFCD06795644

EINECS: 928-470-0

PRODUCT Properties

• Melting point: 214-217°
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: H₂O: soluble
• form: solid
• color: white to off-white
• Merck: 14,6980
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
• CAS DataBase Reference: 78712-43-3(CAS DataBase Reference)

Description and Uses

Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.

Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.

Safety

• RIDADR: 3077
• WGK Germany: 2
• RTECS: UD3380000
• HS Code: 29332900