Ozagrel hydrochloride hydrate , ≥98%(HPLC) , 78712-43-3
Synonym(s):
(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate;OKY-046
CAS NO.：78712-43-3
Empirical Formula: C13H13ClN2O2
Molecular Weight: 264.71
MDL number: MFCD06795644
EINECS: 928-470-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB164.00 | In Stock |
|
| 5G | RMB186.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 214-217° |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | H2O: soluble |
| form | solid |
| color | white to off-white |
| Merck | 14,6980 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month. |
Description and Uses
Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.
Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.
Safety
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | UD3380000 |
| HS Code | 29332900 |
