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A6536812

Omeprazole , 98% , 73590-58-6

Synonym(s):
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole;Antra;Losec;Omeprazole

CAS NO.:73590-58-6

Empirical Formula: C17H19N3O3S

Molecular Weight: 345.42

MDL number: MFCD00083192

EINECS: 615-996-8

Pack Size Price Stock Quantity
1G RMB24.00 In Stock
5G RMB47.20 In Stock
25G RMB126.40 In Stock
100g RMB385.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 156°C
Boiling point: 600.0±60.0 °C(Predicted)
Density  1.332 g/cm3
Flash point: 9℃
storage temp.  2-8°C
solubility  H2O: 0.5 mg/mL
pka pKa 4.14/8.9(H2O,t =25,I=0.025) (Uncertain)
form  solid
color  white
Water Solubility  Soluble in water (0.5 mg/ml), DMSO (25 mg/ml), and ethanol (4.5 mg/ml).
Merck  14,6845
BCS Class 2
Stability: Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark.
InChIKey SUBDBMMJDZJVOS-UHFFFAOYSA-N
CAS DataBase Reference 73590-58-6(CAS DataBase Reference)
EPA Substance Registry System 1H-Benzimidazole, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]- (73590-58-6)

Description and Uses

Omeprazole is a potent gastric antisecretory agent with selective inhibitory effect on the H+,K+-ATPase proton pump. It is highly effective in the treatment of duodenal ulcer and Zollinger-Ellison syndrome, and is reportedly superior to ranitidine in the management of reflux esophagitis.

Omeprazole is a proton pump inhibitor used to treat diseases like gastroesophageal reflux disease (GERD), used for gastric and duodenal ulcers, reflux or erosive esophagitis, and Zollinger-Ellison syndrome. It is also effective for gastric and duodenal ulcers that are ineffective with H2 receptor antagonists. Injections of Omeprazole can also be used for: 1 gastrointestinal bleeding, such as peptic and anastomic ulcer bleeding, and the prevention of severe diseases (such as cerebral hemorrhage, severe trauma, etc.) and gastric surgery caused by upper intestinal bleeding; 2 acute gastric mucosal damage complicated by stress or nonsteroidal anti-inflammatory drugs; 3 general anesthesia, post-surgery, or coma patients, to prevent acid reflux and aspiration pneumonia; 4 Combined with amoxicillin and clarithromycin, or with metronidazole and clarithromycin, it can effectively kill Helicobacter pylori (Hp).

Safety

Symbol(GHS) 
GHS02,GHS06,GHS08,GHS07
Signal word  Danger
Hazard statements  H303-H225-H301+H311+H331-H370-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P405-P501a-P210-P260-P280-P301+P310-P311-P305+P351+P338-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-39/23/24/25-23/24/25-11
Safety Statements  26-36-37/39-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  DD9087000
HS Code  29333990
Hazardous Substances Data 73590-58-6(Hazardous Substances Data)
Toxicity LD50 in mice, rats (g/kg): 0.08, >0.05 i.v.; >4, >4 orally (Ekman)

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