Oxytetracycline hydrochloride , BP2007, medicinal level , 2058-46-0

Synonym(s):
5-Hydroxytetracycline hydrochloride;OTC;Oxytetracycline hydrochloride;Oxytetracycline, Hydrochloride - CAS 2058-46-0 - Calbiochem

CAS NO.：2058-46-0

Empirical Formula: C22H25ClN2O9

Molecular Weight: 496.89

MDL number: MFCD00135815

EINECS: 218-161-2

PRODUCT Properties

• Melting point: 180°C
• alpha: -188～-200°(D/20℃)(c=1,0.1mol/l HCl) (calculated on the dried basis)
• storage temp.: 0-6°C
• solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent). Solutions in water become turbid on standing, owing to the precipitation of oxytetracycline.
• form: crystalline
• color: yellow
• PH: 2.0～3.0 (10g/l, 25℃)
• Water Solubility: >100 g/L
• Sensitive: Light Sensitive
• λmax: 360nm(H2O)(lit.)
• Merck: 14,6976
• BRN: 3853107
• Stability: Hygroscopic

Description and Uses

Oxytetracycline is a tetracycline analog isolated from the actinomycete Streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells and antibiotic susceptibilities of Mycoplasma bovis isolates.

Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H361fd
• Precautionary statements: P201-P202-P280-P308+P313-P405-P501
• Hazard Codes: Xn,Xi
• Risk Statements: 63
• Safety Statements: 45-53-36/37/39
• WGK Germany: 2
• RTECS: QI8225000
• F: 8-10-23
• TSCA: Yes
• HS Code: 29413000
• Toxicity: LD50 oral in mouse: 6696mg/kg