Ofloxacin , Analysis of standard products, ≥99.0%(HPLC) , 82419-36-1

CAS NO.：82419-36-1

Empirical Formula: C18H20FN3O4

Molecular Weight: 361.37

MDL number: MFCD00226105

EINECS: 680-263-1

PRODUCT Properties

• Melting point: 270-2750C
• Boiling point: 571.5±50.0 °C(Predicted)
• Density: 1.2688 (estimate)
• storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• solubility: 1 M NaOH: soluble50mg/mL
• pka: 5.19±0.40(Predicted)
• form: Solid
• color: Colorless needles from ethanol
• Water Solubility: Soluble in acetic acid or water. Slightly soluble in methanol
• λmax: 326nm(H2O)(lit.)
• Merck: 14,6771
• BCS Class: 1
• CAS DataBase Reference: 82419-36-1(CAS DataBase Reference)
• EPA Substance Registry System: Ofloxacin (82419-36-1)

Description and Uses

Ofloxacin is an antibacterial agent with increased potency in comparison to the prototype third generation quinolone, norfloxacin. It has a broad spectrum of activity against gram-positive and gram-negative bacteria and is useful in the treatment of kidney, genitourinary, and upper respiratory tract infections.

Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H303
• Precautionary statements: P270-P301+P312-P403-P501c
• Hazard Codes: Xn,Xi
• Risk Statements: 22-42/43-68-36/37/38
• Safety Statements: 26-36/37/39-24/25-22-37/39-60
• WGK Germany: 3
• RTECS: UU8815550
• HS Code: 29349990
• Hazardous Substances Data: 82419-36-1(Hazardous Substances Data)
• Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 5450, 5290, 3590, 3750 orally; 208, 233, 273, 276 i.v.; >10000, >10000, 7070, 9000 s.c. (Ohno)