Valproic acid , ≥98.0% , 99-66-1
Synonym(s):
2-Propylpentanoic acid;2-Propylvaleric acid;Dipropylacetic acid, Valproic acid, 2-Propylpentanoic acid;Valproic acid
CAS NO.：99-66-1
Empirical Formula: C8H16O2
Molecular Weight: 144.21
MDL number: MFCD00002672
EINECS: 202-777-3
| Pack Size | Price | Stock | Quantity |
| 25ml | RMB52.00 | In Stock |
|
| 100ml | RMB150.40 | In Stock |
|
| 500ml | RMB641.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | -21.25°C (estimate) |
| Boiling point: | 220 °C (lit.) |
| Density | 0.9 g/mL at 25 °C (lit.) |
| vapor pressure | 0.01 hPa (20 °C) |
| refractive index | n |
| Flash point: | 232 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: slightly soluble |
| form | Liquid |
| pka | 4.6(at 25℃) |
| color | Clear colorless to pale yellow |
| Odor Threshold | 0.0033ppm |
| explosive limit | 1%(V) |
| Water Solubility | slightly soluble |
| Merck | 14,9913 |
| BRN | 1750447 |
| BCS Class | 1,2 |
| LogP | 1.59 at 22.1℃ and pH5 |
| CAS DataBase Reference | 99-66-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Valproic Acid(99-66-1) |
| EPA Substance Registry System | Valproic acid (99-66-1) |
Description and Uses
Valproic acid and its salts are a new group of antiepileptic drugs that differs from the
known drugs both structurally and in terms of its mechanism of action. It is believed that
it acts on the metabolism of the GABA system. Valproic acid has been shown to elevate
the level of GABA in the brain by means of competitive inhibition of GABA transaminase
and the dehydrogenase of succinic semialdehyde.
This drug not only exhibits anticonvulsant action, but also betters the mental condition
of the patient.
Antiepileptic; increases levels of -aminobutyric acid(GABA) in the brain. Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H360D |
| Precautionary statements | P201-P301+P312+P330-P302+P352-P305+P351+P338-P308+P313 |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-36/37/38-39/23/24/25-23/24/25-11-34-61 |
| Safety Statements | 26-45-36/37-16-7-36/37/39-53 |
| RIDADR | UN 1230 3/PG 2 |
| WGK Germany | 3 |
| RTECS | YV7875000 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29159080 |
| Hazardous Substances Data | 99-66-1(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 670 mg/kg (Jenner) |
