Home Categories <i>N</i>-(<i>tert</i>-Butoxycarbonyl)-1,5-diaminopentane
A6324512

<i>N</i>-(<i>tert</i>-Butoxycarbonyl)-1,5-diaminopentane , >98.0%(T) , 51644-96-3

Synonym(s):
N-Boc-1,5-diaminopentane;tert-Butyl N-(5-aminopentyl)carbamate

CAS NO.:51644-96-3

Empirical Formula: C10H22N2O2

Molecular Weight: 202.29

MDL number: MFCD00210020

Pack Size Price Stock Quantity
1G RMB108.00 In Stock
5G RMB328.00 In Stock
10g RMB639.20 In Stock
25G RMB1543.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 309.2±25.0 °C(Predicted)
Density  0.972 g/mL at 20 °C(lit.)
refractive index  n20/D 1.460
Flash point: 109 °C
storage temp.  Keep in dark place,Sealed in dry,2-8°C
pka 12.91±0.46(Predicted)
form  Oil
color  Yellow
BRN  3603658
InChIKey DPLOGSUBQDREOU-UHFFFAOYSA-N
CAS DataBase Reference 51644-96-3(CAS DataBase Reference)

Description and Uses

tert-Butyl (5-aminopentyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-Butyl (5-aminopentyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

N-Boc-cadaverine is an intermediate in the synthesis of derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 2735 8/PG 3
WGK Germany  3
10-34
HazardClass  8
PackingGroup 
HS Code  2924190090

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