<i>N</i>-(<i>tert</i>-Butoxycarbonyl)-1,5-diaminopentane , >98.0%(T) , 51644-96-3

Synonym(s):
N-Boc-1,5-diaminopentane;tert-Butyl N-(5-aminopentyl)carbamate

CAS NO.：51644-96-3

Empirical Formula: C10H22N2O2

Molecular Weight: 202.29

MDL number: MFCD00210020

PRODUCT Properties

• Boiling point: 309.2±25.0 °C(Predicted)
• Density: 0.972 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.460
• Flash point: 109 °C
• storage temp.: Keep in dark place,Sealed in dry,2-8°C
• pka: 12.91±0.46(Predicted)
• form: Oil
• color: Yellow
• BRN: 3603658
• InChIKey: DPLOGSUBQDREOU-UHFFFAOYSA-N

Description and Uses

tert-Butyl (5-aminopentyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-Butyl (5-aminopentyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

N-Boc-cadaverine is an intermediate in the synthesis of derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
• Hazard Codes: C
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• F: 10-34
• HazardClass: 8
• PackingGroup: Ⅲ
• HS Code: 2924190090