Home Categories Biochemical Engineering <i>N</i><sup>&epsilon;</sup>-Acetyl-<small>L</small>-lysine
A6311412

<i>N</i><sup>&epsilon;</sup>-Acetyl-<small>L</small>-lysine , >98.0%(T) , 692-04-6

CAS NO.:692-04-6

Empirical Formula: C8H16N2O3

Molecular Weight: 188.22

MDL number: MFCD00002639

EINECS: 211-725-9

Pack Size Price Stock Quantity
1G RMB128.00 In Stock
5G RMB308.00 In Stock
25g RMB1096.00 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 250 °C (dec.)(lit.)
Boiling point: 323.23°C (rough estimate)
Density  1.1793 (rough estimate)
refractive index  1.4500 (estimate)
storage temp.  -20°C
solubility  Aqueous Base (Slightly), Water (Slightly)
pka 2.53±0.24(Predicted)
form  Powder
color  White
Water Solubility  Soluble in water (miscible), and 80% acetic acid (50 mg/ml).
Sensitive  Hygroscopic
InChIKey DTERQYGMUDWYAZ-ZETCQYMHSA-N

Description and Uses

Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.

N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  29241900

RELATED PRODUCTS