N-Fmoc-4-methoxy-L-phenylalanine , 95% , 77128-72-4

Synonym(s):
Fmoc-Tyr(Me)-OH;N-α-Fmoc-O-methyl-L-tyrosine

CAS NO.：77128-72-4

Empirical Formula: C25H23NO5

Molecular Weight: 417.45

MDL number: MFCD00153368

PRODUCT Properties

• Melting point: 161 °C
• Boiling point: 647.8±55.0 °C(Predicted)
• Density: 1.274±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,2-8°C
• form: powder to crystal
• pka: 2.97±0.10(Predicted)
• color: White to Almost white
• InChIKey: JYQODLWFOPCSCS-QHCPKHFHSA-N
• SMILES: C(O)(=O)[C@H](CC1=CC=C(OC)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
• CAS DataBase Reference: 77128-72-4(CAS DataBase Reference)

Description and Uses

Fmoc-Tyr(Me)-OH, also known as Fmoc-O-methyl-L-tyrosine, is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319-H335-H315
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
• WGK Germany: WGK 2 water endangering
• HazardClass: IRRITANT
• HS Code: 29242990