Nobiletin , Analysis standard , 478-01-3
Synonym(s):
2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one;3′,4′,5,6,7,8-Hexamethoxyflavone
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB4367.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 136.0 to 140.0 °C |
| Boiling point: | 587.9±50.0 °C(Predicted) |
| Density | 1.244±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 10 mg/ml) |
| form | Solid |
| color | White |
| BRN | 360887 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | MRIAQLRQZPPODS-UHFFFAOYSA-N |
| CAS DataBase Reference | 478-01-3(CAS DataBase Reference) |
Description and Uses
Nobiletin (478-01-3) is a natural product isolated from citrus peels.? It has recently been shown to possess circadian clock amplitude-enhancing properties and was able to prevent metabolic syndrome in mice?via?a?Clock?gene-dependent mechanism.1? Nobiletin directly bound to and activated RORα/γ.? Nobiletin has previously been shown to attenuate the effects of metabolic syndrome2, have anti-neuroinflammatory effects3, possess neurotrophic activity4, and be a cancer chemopreventative agent5.
Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein.
Safety
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | DJ3052200 |
| HS Code | 29329990 |
