5-Nitroindole , 98% , 6146-52-7

Synonym(s):
NSC 520594

CAS NO.：6146-52-7

Empirical Formula: C8H6N2O2

Molecular Weight: 162.15

MDL number: MFCD00005673

EINECS: 228-153-0

PRODUCT Properties

• Melting point: 140-142 °C (lit.)
• Boiling point: 288.82°C (rough estimate)
• Density: 1.3264 (rough estimate)
• refractive index: 1.5770 (estimate)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Dichloromethane, Ethyl Acetate, Methanol
• pka: 15.25±0.30(Predicted)
• form: Crystalline Powder or Needles
• color: Yellow
• BRN: 383777
• InChI: InChI=1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
• InChIKey: OZFPSOBLQZPIAV-UHFFFAOYSA-N
• SMILES: N1C2=C(C=C([N+]([O-])=O)C=C2)C=C1
• CAS DataBase Reference: 6146-52-7(CAS DataBase Reference)

Description and Uses

Reactant for preparation of:

• Pharmaceutically active 2-oxo-1-pyrrolidine analogues
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Protein Kinase Inhibitors and antiproliferative agents
• Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
• Antifungal agents
• Cannabinoid receptor type 1 (CB1) antagonists
• Potential anticancer agents
• Potential antivascular agents
• Selective Anti-leukemic agents
• Anti human immunodeficiency virus subtype 1 (HIV-1) agents

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H318
• Precautionary statements: P280-P301+P312+P330-P305+P351+P338+P310
• Hazard Codes: Xn,Xi
• Risk Statements: 22-41
• Safety Statements: 26-39-45-36/37
• WGK Germany: 3
• RTECS: NM1168200
• F: 8
• Hazard Note: Irritant
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• HS Code: 29339900