β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate , 97% , 1184-16-3

Synonym(s):
β-Nicotinamide adenine dinucleotide phosphate disodium salt;β-NADH phosphate disodium salt;β-NADP-Na₂;β-Nicotinamide-adenine Dinucleotide Phosphate, TPN, Co II, Na;Triphosphopyridine nucleotide disodium salt

CAS NO.：1184-16-3

Empirical Formula: C21H27N7NaO17P3

Molecular Weight: 765.39

MDL number: MFCD00036973

EINECS: 214-664-6

PRODUCT Properties

• Melting point: 175-178 °C (dec.)(lit.)
• storage temp.: -20°C
• solubility: H₂O: 50 mg/mL
• form: powder
• color: off-white to yellow
• PH: 2.0-4.0
• Water Solubility: Soluble in water.
• Merck: 14,6344
• BRN: 4779954
• InChIKey: JNUMDLCHLVUHFS-QYZPTAICSA-M

Description and Uses

The nicotinamide adenine dinucleotide phosphate oxidase（NADP）is a multicomponent system that transfers an electron to molecular oxygen by way of FAD and heme to form superoxide (O2?) .Cytochrome b558 is a membrane-bound heterodimer lodged in the wall of the secondary granules; the large glycosylated β subunit is gp91phox and the small nonglycosylated α subunit is p22phox.The cytoplasmic tail of gp91phox binds FAD, heme, and NADPH, which are required for electron transfer to oxygen (O2).Neutrophil stimulation leads to aggregation and phosphorylation of p47phox, p67phox, p40phox, and the small guanosine triphosphate (GTP)–binding proteins RAC1/RAC2, which dock with the cytochrome at the membrane through binding of p47phox and p22phox.

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions.
β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate is a substrate NADP which plays a role in a variety of metabolic processes.

Safety

• Hazard Codes: Xn,Xi
• Risk Statements: 36-36/37/38
• Safety Statements: 22-24/25-37/39-36-26
• WGK Germany: 3
• RTECS: UU3440000
• HS Code: 29349990