Methyl Thiocyanate , 98% , 556-64-9

Synonym(s):
Thiocyanic acid methyl ester

CAS NO.：556-64-9

Empirical Formula: C2H3NS

Molecular Weight: 73.12

MDL number: MFCD00001830

EINECS: 209-134-6

Update time: 2022-07-08

PRODUCT Properties

Melting point:	-5 °C
Boiling point:	131 °C
Density	1.08
refractive index	1.467-1.469
Flash point:	38 °C
storage temp.	Poison room
Water Solubility	Practically insoluble in water
solubility	Chloroform (Soluble), Methanol (Slightly)
form	Liquid
color	Clear colorless to light yellow
Odor	at 0.01?%?in?propylene glycol. sulfury onion
Sensitive	Moisture Sensitive
Merck	14,6127
Dielectric constant	4.3（19℃）
LogP	0.502 (est)

Description and Uses

Methyl thiocyanate is a colorless liquid withan onion-like odor. Molecular weight = 73.12; Boilingpoint= 130-133℃; Freezing/Melting point= - 51℃.Very slightly soluble in water.

Methyl thiocyanate is a reagent that is used in the synthesis of WAK 4103 (W498200), which is a metabolite of Imidacloprid (I274990), a neonicotinoid; the active ingredient in certain neuro-active insecticides. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.Nauen, R., et. al.: Pestic. Sci., 55, 265 (1999); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009); Patial, A., et al.: Env. Ecol., 27, 320 (2009); Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009); Chem. and Eng. News 90: 10 (2012)

Safety

Symbol(GHS)	GHS02,GHS06
Signal word	Danger
Hazard statements	H226-H301+H311+H331-H319-H335
Precautionary statements	P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338
Hazard Codes	T
Risk Statements	23/24/25-10-36/37
Safety Statements	28A-27-26-16-45-36/37/39
RIDADR	UN1992
WGK Germany	3
RTECS	XL1575000
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29309099
Toxicity	LD50 i.p. in mice: 315 nmoles/g (Ohkawa)