4'-Methylacetophenone , 95% , 122-00-9

Synonym(s):
4′-Methylacetophenone;Methyl p-tolyl ketone;Methyl p-tolyl ketone

CAS NO.：122-00-9

Empirical Formula: C9H10O

Molecular Weight: 134.18

MDL number: MFCD00008751

EINECS: 204-514-8

PRODUCT Properties

• Melting point: 22-24 °C (lit.)
• Boiling point: 226 °C (lit.)
• Density: 1.004 g/mL at 20 °C 1.005 g/mL at 25 °C (lit.)
• vapor pressure: 0.52 hPa (25 °C)
• FEMA: 2677 | 4'-METHYLACETOPHENONE
• refractive index: n20/D 1.533(lit.)
• Flash point: 198 °F
• storage temp.: Store below +30°C.
• solubility: 2.07g/l
• form: Liquid
• color: Clear colorless to pale yellow
• Odor: at 10.00 % in dipropylene glycol. hawthorn sweet mimosa coumarin cherry acetophenone
• Odor Type: floral
• explosive limit: 1.00%(V)
• Water Solubility: 0.37 g/L (15 ºC)
• JECFA Number: 807
• BRN: 606053
• InChIKey: GNKZMNRKLCTJAY-UHFFFAOYSA-N
• LogP: 2.1 at 25℃

Description and Uses

4'-Methylacetophenone has a fruity, floral odor resembling acetophenone and a sweet, strawberry-like flavor. May be prepared by slow addition of acetyl chloride to a mixture of toluene and AlCl in an ice bath and under vacuum, maintaining the temperature at +5°C and then letting it increase to +20°C.

4'-Methylacetophenone is used as a flavoring agent. It reacts with morpholine to get 4-(p-tolyl-thioacetyl)-morpholine in the presence of sulfur as a reagent. Further, it is used as an intermediate in the manufacture of active pharmaceutical ingredients, perfumes and cosmetics.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315
• Precautionary statements: P264-P270-P280-P301+P312-P302+P352-P332+P313
• Hazard Codes: Xn
• Risk Statements: 36/37/38-22-20/21/22
• Safety Statements: 26-27-37/39-24/25-23-36
• RIDADR: UN 1325 4.1/PG 2
• WGK Germany: 3
• RTECS: AM9463000
• TSCA: Yes
• HS Code: 29143900
• Toxicity: LD50 orally in Rabbit: 1400 mg/kg LD50 dermal Rabbit > 2000 mg/kg