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A5572612

Marbofloxacin , 98% , 115550-35-1

Synonym(s):
9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid;Zeniquin

CAS NO.:115550-35-1

Empirical Formula: C17H19FN4O4

Molecular Weight: 362.36

MDL number: MFCD00864820

EINECS: 640-416-5

Pack Size Price Stock Quantity
1G RMB109.60 In Stock
5G RMB307.20 In Stock
25G RMB1166.40 In Stock
100g RMB4080.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 268-269°C (dec.)
Boiling point: 571℃
Density  1.55±0.1 g/cm3(Predicted)
Flash point: >110°(230°F)
storage temp.  Inert atmosphere,2-8°C
solubility  Chloroform (Slightly, Heated)
pka 6.02±0.20(Predicted)
form  Solid
color  Light Yellow
Water Solubility  Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml
Merck  14,5750
InChI InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
InChIKey BPFYOAJNDMUVBL-UHFFFAOYSA-N
SMILES N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C

Description and Uses

Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.

A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
Hazard Codes  Xi
Risk Statements  52/53-36/37/38
Safety Statements  61-36-26-60
WGK Germany  2
RTECS  UU8815140
HS Code  29349990

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