2-[Methyl(phenylmethyl)amino]ethanol , 90% , 101-98-4

Synonym(s):
2-(N-Benzyl-N-methylamino)ethanol

CAS NO.：101-98-4

Empirical Formula: C10H15NO

Molecular Weight: 165.23

MDL number: MFCD00002847

EINECS: 202-994-3

PRODUCT Properties

• Boiling point: 95-105 °C2 mm Hg(lit.)
• Density: 1.017 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.529(lit.)
• Flash point: >230 °F
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 14.75±0.10(Predicted)
• form: Oil
• color: Colourless
• BRN: 366412
• CAS DataBase Reference: 101-98-4(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-[methyl(phenylmethyl)amino]-(101-98-4)
• EPA Substance Registry System: Ethanol, 2-[methyl(phenylmethyl)amino]- (101-98-4)

Description and Uses

N-Benzyl-N-methylethanolamine is a surfactant that has a high capacity for adsorbing proteins. It is used as an efficient method to remove impurities from human immunoglobulin preparations and as an adsorbent in chromatographic methods. N-Benzyl-N-methylethanolamine has also been used as a diagnostic agent for the detection of chromatographically separated monoclonal antibodies, which are produced by activated B cells in culture. The antibody binds to the target protein and then the antibody-protein complex is isolated using a particle agglomeration technique. This method can be repeated multiple times and produce high concentrations of pure monoclonal antibodies.

2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39-24/25
• WGK Germany: 3
• HS Code: 29214990