Bromobimane , ≥95.0% , 71418-44-5
Synonym(s):
THIOLYTE MB Reagent, MBB
CAS NO.：71418-44-5
Empirical Formula: C10H11BrN2O2
Molecular Weight: 271.11
MDL number: MFCD00036951
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB414.40 | In Stock |
|
| 25MG | RMB799.20 | In Stock |
|
| 100MG | RMB2399.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 152-154 °C(lit.) |
| Boiling point: | 327.8±44.0 °C(Predicted) |
| Density | 1.66±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: soluble |
| pka | -3.36±0.70(Predicted) |
| form | powder |
| color | Yellow |
| λmax | 398 nm |
| BRN | 4430959 |
| Stability: | Light Sensitive |
| Biological Applications | Glutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes |
| CAS DataBase Reference | 71418-44-5 |
Description and Uses
Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.
Monobromobimane readily reacts with low molecular weight thiols. Bimanes are useful for detecting the distribution of protein thiols in cells before and after chemical reduction of disulfides. Fluorescence: max. Abs. 398nm; e x 10-3: 5.0
