Home Categories API Meclizine 2HCl
A5524112

Meclizine 2HCl , ≥98% , 1104-22-9

Synonym(s):
1-([4-Chlorophenyl]phenylmethyl)-4-([3-methylphenyl]methyl)piperazine;1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-piperazine dihydrochloride;1-[(4-Chlorophenyl)phenylmethyl]4-[?(3-methylphenyl)methyl]piperazine dihydrochloride;Meclizine dihydrochloride;NSC 28728

CAS NO.:1104-22-9

Empirical Formula: C25H29Cl3N2

Molecular Weight: 463.87

MDL number: MFCD00058199

EINECS: 214-164-8

Pack Size Price Stock Quantity
250mg RMB34.40 In Stock
1G RMB89.60 In Stock
5G RMB272.00 In Stock
25G RMB819.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 210.0 to 214.0 °C
storage temp.  2-8°C
solubility  DMSO: soluble5mg/mL, clear (warmed)
form  powder
color  white to beige

Description and Uses

Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM). Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung. Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.

Meclizine Dihydrochloride is a histamine H1 receptor antagonist with antiemetic properties. Meclizine Dihydrochloride is a research product for neuroscience. This compound may exhibit neuroprotective properties.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361
Precautionary statements  P201-P301+P312+P330-P308+P313
Hazard Codes  Xn
Risk Statements  22-63
Safety Statements  22-36
WGK Germany  3
RTECS  TL2005000
HS Code  2933.59.8000
Toxicity LD50 oral in mouse: 1600mg/kg

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