Home Categories Organic Chemistry 5-Methoxytryptamine
A5512512

5-Methoxytryptamine , 97% , 608-07-1

Synonym(s):
5-Methoxytryptamine;5-Methoxytryptamine hydrochloride;2-(5-Methoxyindol-3-yl)ethylamine;3-(2-Aminoethyl)-5-methoxyindole;5-MOT

CAS NO.:608-07-1

Empirical Formula: C11H14N2O

Molecular Weight: 190.24

MDL number: MFCD00005662

EINECS: 210-153-7

Pack Size Price Stock Quantity
250MG RMB19.20 In Stock
1G RMB23.20 In Stock
5G RMB31.20 In Stock
25G RMB86.40 In Stock
100g RMB317.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 121-123 °C (lit.)
Boiling point: 325.75°C (rough estimate)
Density  1.0815 (rough estimate)
refractive index  1.5700 (estimate)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  crystalline
pka 16.91±0.30(Predicted)
color  white
Merck  13,6032
BRN  145587
InChI InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
InChIKey JTEJPPKMYBDEMY-UHFFFAOYSA-N
SMILES N1C2=C(C=C(OC)C=C2)C(CCN)=C1
CAS DataBase Reference 608-07-1(CAS DataBase Reference)
NIST Chemistry Reference 5-Methoxytryptamine(608-07-1)

Description and Uses

5-Methoxytryptamine (5-MT), also known as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. 5-MT has been shown to occur naturally in the body in low levels.It is biosynthesized via the deacetylation of melatonin in the pineal gland.
The protective effect of 5-methoxytryptamine (a metabolite of melatonin) in human keratinocytes against ultraviolet B (UVB) radiation was studied.
Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.

5-Methoxytryptamine (Mexamine, Methoxytryptamine) is a tryptamine derivative that is closely related to the neurotransmitter Melatonin (M215000) and Serotonin (S274980). It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors but has no affinity for the 5-HT3 receptor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  36-26
WGK Germany  3
RTECS  NL4110000
8
HS Code  29339900
Toxicity LD50 intraperitoneal in mouse: 176mg/kg

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