(S)-(-)-2-Methyl-2-propanesulfinamide , 98% , 343338-28-3

CAS NO.：343338-28-3

Empirical Formula: C4H11NOS

Molecular Weight: 121.2

MDL number: MFCD05861480

EINECS: 640-158-3

PRODUCT Properties

• Melting point: 97-101 °C(lit.)
• alpha: -4.5 º (c=1, CHCl3)
• Boiling point: 220.0±23.0 °C(Predicted)
• Density: 1.124
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 10.11±0.50(Predicted)
• form: Crystalline Powder
• color: White
• optical activity: [α]20/D 4.5°, c = 1 in chloroform
• Stability: store cold
• InChI: InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
• InChIKey: CESUXLKAADQNTB-SSDOTTSWSA-N
• SMILES: CC(C)([S@@](N)=O)C |&1:3,r|

Description and Uses

(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280-P305+P351+P338-P304+P340-P405-P501A
• Hazard Codes: Xi,Xn,F
• Risk Statements: 11-19-36/37-40
• Safety Statements: 16-26-36/37-24/25
• WGK Germany: 3
• Hazard Note: Irritant/Keep Cold
• TSCA: No
• HS Code: 29309090