Home Categories Biochemical Engineering Magnolol
A5428312

Magnolol , Analysis of standards,> 98% , 528-43-8

Synonym(s):
2,2′-Bichavicol;5,5′-Diallyl-2,2′-biphenyldiol

CAS NO.:528-43-8

Empirical Formula: C18H18O2

Molecular Weight: 266.33

MDL number: MFCD00016658

EINECS: 610-903-7

Pack Size Price Stock Quantity
20MG RMB71.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 101.5-102°
Boiling point: 180°C/1mmHg(lit.)
Density  1.107±0.06 g/cm3(Predicted)
FEMA  4559 | MAGNOLOL
storage temp.  Sealed in dry,2-8°C
solubility  ethanol: soluble1mg/mL
pka 9.49±0.43(Predicted)
form  Solid
color  White to Almost white
Odor bitter
λmax 292nm(EtOH)(lit.)
JECFA Number 2023
Merck  14,5697
Stability: Light Sensitive
LogP 4.502 (est)

Description and Uses

Magnolol is a bioactive compound isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases. Magnolol can activate cannabinoid (CB) receptors, behaving as a partial agonist with selectivity for the peripheral CB2 subtype (EC50 = 3.28 μM; Ki = 1.44 μM) versus central CB1 (EC50 = 18.3 μM; Ki = 3.15 μM).

Magnolol is the bioactive phytochemicals found in Magnolia officinalis (1). Magnolol has been used to treat anxiety, cough, headache and allergies (2). It also inhibits tumor necrosis factor-a-*induced ICAM-1 expression in human lung epithelial cells.

Safety

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H315-H318-H335-H411
Precautionary statements  P273-P280-P302+P352-P305+P351+P338+P310
Hazard Codes  N
Risk Statements  37/38-41-51/53
Safety Statements  26-39-61
RIDADR  UN 3077
WGK Germany  3
RTECS  DV5105500
HS Code  29072990
Toxicity LD50 orl-mus: 2200 mg/kg BRXXAA #5135746

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